Major tourist destinations in the region include the historic, cultural and artistic cities of Milan (which is Italy's second top tourist destination), Brescia, Mantua, Pavia, Como, Cremona, Bergamo, Sondrio, Lecco, Lodi, Varese, Monza, and the lakes of Garda, Como, Maggiore, and Iseo.
Lombardy is bordered by Switzerland (north: Canton Ticino and Canton Graubünden) and by the Italian regions of Emilia-Romagna (south), Trentino-Alto Adige/Südtirol and the Veneto (east), and Piedmont (west). Three distinct natural zones can be fairly easily distinguished in the Lombardy region: mountains, hills and plains – the latter being divided in Alta (high plains) and Bassa (low plains).
The great Lombard lakes, all of glacial origin lie in this zone. From west to east these are Lake Maggiore, Lake Lugano (only a small part is Italian), Lake Como, Lake Iseo, Lake Idro, then Lake Garda, the largest in Italy. South of the Alps lie the hills characterized by a succession of low heights of morainic origin, formed during the last Ice Age and small barely fertile plateaux, with typical heaths and conifer woods. A minor mountainous area lies south of the Po, in the Appennines range.